Hi,
What is the gender changer doing?
Apparently not what you need it to
You are the one with the gender changer on your table, so just unscrew it and see if the full set of wires are really mounted correctly.
Not knowing exactly what your needs are (or the needs of the USB/serial converter), but check your documentation to see if you need a null modem wiring (which is more than just swapping TX and RX).