Two accelerometers and magnetometers -- one on the palm, and one on the forearm -- would let you calculate relative orientations, which would in turn let you calculate how much the wrist is bent. The magnetometers may actually be best for this, as they don't see additional forces because of the movement itself.
Another option is to buy something that already does what you want. There are various kinds of "gamer gloves" around that may already suit your needs.