Hi,
If you want to make the finished piece directly on the positive mold (without the intermediate negative), I see no problem in letting the plastic stick, as you can just sand it off afterward if it bothers you.
Not using a negative mold means a lot more finishing work with sanding etc. with perhaps a top layer of GelCoat. Using a negative mold, you start off with a couple of layers of GelCoat before using glass cloth at all and if you had a smooth positive to make the negative from, you will have a just as smooth finish.